• About Herbs, Botanicals & Other Products
  Memorial Sloan-Kettering Cancer Center
• Consumer Directed Questions and Answers about FDA’s Initiative Against Contaminated Weight Loss Products
  U.S. Food and Drug Administration
• Dietary Supplements
  Center for Food Safety and Applied Nutrition, U.S. Food and Drug Administration
• Dietary Supplements
  Food and Nutrition Information Center, National Agricultural Library
• Dietary Supplements: Background Information
  Office of Dietary Supplements, National Institutes of Health
• Herbal Dietary Supplements: Examples of Deceptive or Questionable Marketing Practices and Potentially Dangerous Advice (PDF, 500 KB)
  United States Government Accountability Office
• Multivitamin/Mineral Supplements and Prevention of Chronic Disease (PDF, 3 MB)
  Evidence Report/Technology Assessment Number 139. Agency for Healthcare Research and Quality, U.S. Department of Health and Human Services
• National Institutes of Health State-of-the-Science Conference Statement: Multivitamin/Mineral Supplements and Chronic Disease Prevention
  NIH State-of-the-Science Panel. Ann Intern Med. 2006 Sep 5;145(5):364-71.
• Tips For The Savvy Supplement User: Making Informed Decisions and Evaluating Information
  Center for Food Safety and Applied Nutrition, U.S. Food and Drug Administration
• Using Dietary Supplements Wisely
  National Center for Complementary and Alternative Medicine
• Vitamins & Supplements: Get the Latest FDA Consumer Health Updates
  WebMD and U.S. Food and Drug Administration

Herbs

• Botanical Dietary Supplements: Background Information
  Office of Dietary Supplements, National Institutes of Health
• Herbs & Supplements
  DrugDigest
• Herbs at a Glance
  National Center for Complementary and Alternative Medicine
• Herbal Information
  Food and Nutrition Information Center, National Agricultural Library
• Medicinal Plants in China 1999: A selection of 150 commonly used species (PDF, 7.5 MB)
  World Health Organization
• WHO Monographs on Selected Medicinal Plants, Volume 1 (1999) (PDF, 2.4 MB)
  World Health Organization
• WHO Monographs on Selected Medicinal Plants, Volume 2 (2002) (PDF, 2.6 MB)
  World Health Organization

Supplements

• Medical Guidelines for the Clinical Use of Dietary Supplements and Nutraceuticals (PDF, 950 KB)
  American Association of Clinical Endocrinologists
• Dietary Supplement Fact Sheets
  Office of Dietary Supplements, National Institutes of Health
• Dietary Supplements - Balancing Consumer Choice and Safety (PDF, 1.3 MB)
  Task Force on Life and the Law, New York State Department of Health
• Dietary Supplements Containing Ephedrine Alkaloids
  Center for Food Safety and Applied Nutrition, U.S. Food and Drug Administration
• Evidence-based Reviews, Dietary Supplements
  Agency for Healthcare Research and Quality
• Phytonutrients
  Food and Nutrition Information Center, National Agricutural Library

Vitamins and Minerals

• Vitamins and Minerals
  Food and Nutrition Information Center, National Agricutural Library
• Vitamin and Mineral Supplement Fact Sheets
  Office of Dietary Supplements, National Institutes of Health
• Dietary supplements: Nutrition in a pill?
  MayoClinic.com

Data

• Dietary Reference Intakes for Calcium and Vitamin D (2010)
  Food and Nutrition Board, Institute of Medicine, The National Academies Press, c2010
• Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline
  Food and Nutrition Board, Institute of Medicine, The National Academies Press, c1998
• Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc
  Food and Nutrition Board, Institute of Medicine, The National Academies Press, c2001
• Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids
  Food and Nutrition Board, Institute of Medicine, The National Academies Press, c2000
• Upper Safe Levels of Intake for Adults: Vitamins, Macrominerals, and Trace Minerals
  Nebraska Cooperative Extension

Background

• Overview of Dietary Supplements - What is a dietary supplement?
  U.S. Food and Drug Administration
• Regulatory Framework of DSHEA of 1994
  U.S. Food and Drug Administration

Statute Text

• Government Printing Office PDF text of the Dietary Supplement Health and Education Act of 1994 (DSHEA) (PDF, 68 KB)
  U. S. Government Printing Office

Regulations

• Regulations - 21 CFR Part 101 - Food Labeling
  In Particular Note:
  • 101.14 Health claims: general requirements
  • 101.36 Nutrition labeling of dietary supplements
  • 101.93 Certain types of statements for dietary supplements
  Electronic Code of Federal Regulations

PART 119--Dietary Supplements that Present a Significant or Unreasonable Risk

• 21 CFR Part 119.1 - Dietary supplements containing ephedrine alkaloids
  Electronic Code of Federal Regulations

PART 190--Dietary Supplements

• 21 CFR Part 190.6 - Requirement for premarket notification
  Electronic Code of Federal Regulations

Part 111 Current Good Manufacturing Practice

• Backgrounder: Final Rule for Current Good Manufacturing Practices (CGMPs) for Dietary Supplements
  U.S. Food and Drug Administration
• Current Good Manufacturing Practices (CGMPs)
  U.S. Food and Drug Administration
• 21 CFR Part 111 – Current Good Manufacturing Practice in Manufacturing, Packaging, Labeling, or Holding Operations for Dietary Supplements; Final Rule
  Federal Register / Vol. 72, No. 121 / Monday, June 25, 2007 / Rules and Regulations
• 21 CFR Part 111 – Interim Final Rule: Petition to Request Exemption from 100 Percent Identity Testing of Dietary Ingredients: Current Good Manufacturing Practice in Manufacturing, Packaging, Labeling, or Holding Operations for Dietary Supplements – 21 CFR Part 111 (PDF, 100 KB)
  This interim final rule amends and modifies a portion of the final rule. Federal Register / Vol. 72, No. 121 / Monday, June 25, 2007 / Rules and Regulations

U.S. Food and Drug Administration (FDA) links

• Federal Register Advance Notice of Proposed Rulemaking (Food Labeling) 72 FR 62149 November 2, 2007: Revision of Reference Values and Mandatory Nutrients;
• Labeling & Nutrition
• Dietary Supplement Health and Education Act of 1994
  
  • FDA Label Claims Overview page
  • Claims That Can Be Made for Conventional Foods and Dietary Supplements
  • Dietary Supplement Labeling
  • Guidance for Industry: FDA's Implementation of "Qualified Health Claims": Questions and Answers; Final Guidance
  • Significant Scientific Agreement in the Review of Health Claims for Conventional Foods and Dietary Supplements
  • Structure/Function Claims

• Annual Bibliographies of Significant Advances in Dietary Supplement Research
  Office of Dietary Supplements, National Institutes of Health
• Computer Access to Research on Dietary Supplements (CARDS) Database
  Office of Dietary Supplements, National Institutes of Health
• Dietary Supplements: Resources on Individual Macronutrients, Phytonutrients, Vitamins & Minerals
  Food and Nutrition Information Center, National Agricultural Library
• Dietary Supplements: General Resources for Consumers (PDF, 85 KB)
  Food and Nutrition Information Center, National Agricultural Library
• Dietary Supplements: Additional Resources for Professionals (PDF, 161 KB)
  Food and Nutrition Information Center, National Agricultural Library
• FDA Poisonous Plant Database (March 2006 Update)
  Center for Food Safety and Applied Nutrition, U.S. Food and Drug Administration
• PubMed Dietary Supplement Subset
  National Library of Medicine and the Office of Dietary Supplements, National Institutes of Health

PubMed - Biomedical journal literature

• Dietary Supplements
  
  • Most recent 5 years
  • Review articles
  • All articles on this topic - May retrieve large number of citations
• Herbal or Plant Medicines
  
  • Most recent 5 years
  • Review articles
  • All articles on this topic - May retrieve large number of citations
• Vitamins
  
  • Most recent 5 years
  • Review articles
  • All articles on this topic - May retrieve large number of citations

TOXLINE - Special journal literature, technical reports and archival collections

• Dietary Supplements
  
  • Most recent 5 years
  • Review articles
  • All articles on this topic - May retrieve large number of citations
• Herbal or Plant Medicine
  
  • Most recent 5 years
  • Review articles
  • All articles on this topic - May retrieve large number of citations
• Vitamins
  
  • Most recent 5 years
  • Review articles
  • All articles on this topic - May retrieve large number of citations

MedlinePlus - Consumer Health Information

• Antioxidants
• Dietary Supplements
• Food and Nutrition Topics
• Herbal Medicine
• Herbs and Supplements
• Minerals
• Vitamins

NLM Catalog - Access to information about books and other materials in NLM's catalog

• Dietary Supplements
• Herbal or Plant-based Medicines
• Vitamins

• The American Botanical Council
• Food
  U.S. Food and Drug Administration
• Food and Nutrition Information Center
  National Agricultural Library, U.S. Department of Agriculture
• Office of Dietary Supplements
  Office of the Director, National Institutes of Health

• Afirmaciones sobre Curas "Milagrosas": Añada una Dosis de Escepticismo
  Federal Trade Commission
• ¡Las curas milagrosas pueden ser nocivas para la salud!
  Consumer Action
• Medicina herbaria
  MedlinePlus en español
• Medicinas, hierbas y suplementos
  MedlinePlus en español
• Officina de Suplementos Dietéticos
  Institutos Nacionales de la Salud
• Preguntas Que Hacer Antes de Tomar Vitaminas y Suplementos Minerales
  Nutrition.gov
• Suplementos dietéticos
  Administración de Drogas y Alimentos de los Estados Unidos
• Suplementos en la dieta
  MedlinePlus
• Uso adecuado de los suplementos dietéticos
  National Center for Complementary and Alternative Medicine