SIS News Archive


  • The Community Health Maps (CHM) project team worked with a student intern from the School of Public Health at the University of Maryland in a community health project using tools from the Community Health Maps blog. Like the CHM target audience, the student intern had no experience with GIS or with CHM tools. She analyzed road accessibility around Seabury Assisted Living in downtown Silver Spring, MD by collecting the geo-locations of curb cut-outs in a quarter mile range. The intern developed customized maps with curb cut-outs, combined with layers of roads, sidewalks, and grocery stores, as well as selected census data. The results gathered into an informal walking guide for the Seabury Assisted Living residents. The project also showed that these road construction recommendations may be suitable for presenting to local government. (4/11/2016)
  • Resource lists for Zika Virus Health Information Resources, Aliso Canyon/Porter Ranch Gas Leak (PDF, 454 KB), Lead in Flint, Michigan Water System (PDF, 300 KB) were created. The resources include links to local, state, federal and international agencies and organizations, database searches for health information, and social media resources. (1/28/2016)


  • The National Library of Medicine’s web portal for HIV/AIDS information has been redesigned and given a new name. The new website, AIDSource, offers access to a comprehensive collection of HIV/AIDS-related information resources that are reviewed and selected by expert information specialists and librarians. Visitors to AIDSource will now be able to view the website content on their mobile device. The website is now automatically optimized for display across all device types, including desktop computers, tablets, and smartphones. Feedback received through a website survey conducted in 2014 contributed to the design of the website. In addition to responsive design, the new AIDSource design also includes the following new features: 1) Addition of a slider feature that highlights resources of interest; 2) Addition of images for topics; and 3)Improvements in website navigation, including a menu on all pages of the website that provides access to all topic areas (9/28/2015)
  • Both versions of TOXMAP—classic and beta—now include the Toxics Release Inventory (TRI) 2013 National Analysis data, as well as recent cancer and disease mortality data from NCI SEER. This is the first version of the TOXMAP beta with health data, whereas mortality data in TOXMAP classic has been updated. (4/22/2015)
  • TOXinvaders is an environmental health and toxicology game for iPhone and iPad. It is available from the Apple Store. TOXinvaders supports middle school science concepts pertaining to chemistry, the environment, and health. It can serve as an engaging classroom or homework activity for middle and high school students, as well as an entertaining learning activity for gaming aficionados of all ages. In the classroom environment, TOXinvaders works best as a supplement to NLM Tox Town, Environmental Health Student Portal, TOXMAP, and ChemIDplus Web sites.(3/25/2015)


  • TOXMAP beta now includes 2013 coal emissions data published by the US EPA's Clean Air Markets program. Data was obtained from the Air Markets Program Data (AMPD) tool, a publicly-available data system for searching and downloading data collected as part of EPA's emissions trading programs. (12/8/2014)
  • CHEMM (Chemical Hazards Emergency Management) updated with 1) enhanced content on Decontamination Procedures, Discovering the Event, and Training and Education, 2) an NIH CounterACT program funded database with information on twenty-two medical countermeasures, 3) content for how emergency responders can recognize and handle events dealing with toxic gases generated by the combinations of consumer products or common household chemicals, 4) a workshop report describing toxic chemical syndromes, or toxidromes, that lays the foundation for a consistent lexicon for use in CHEMM and for other uses that, if adopted widely, will improve response to chemical mass exposure incidents, 5) a toxidromes outreach plan whose goal is to raise widespread awareness and encourage use of the toxidromes throughout the stakeholder community, and 6) an evaluation and validation plan for CHEMM's Intelligent Syndromes Tool (CHEMM-IST) that, once completed, will move CHEMM-IST from its current state as a prototype to a product ready for use in an operational response environment.(10/31/2014)
  • The TOXNET and Beyond: Using The NLM Environmental Health and Toxicology Portal (PDF, 8.8 MB) workbook was updated to match the redesigned TOXNET system of databases. (11/5/2014)
  • NLM updated Haz-Map with 497 agents. It now contains 10,133 biological and chemical agents. (8/28/2014)
  • Customer Survey for the NLM HIV/AIDS Portal. (6/10/2014)
  • TOXMAP beta now includes the Toxics Release Inventory (TRI) 2012 National Analysis data. (6/12/2014)
  • WISER with Help Identify Chemical capability is now available on the Android platform. It identifies and validates an unknown chemical based on the following criteria: *Physical properties of the substance gathered by observation or sensors. *Signs and symptoms of victims of exposure. *The ability to categorize a substance, such as a substance used in a meth lab or a flammable substance. *Hazard values from NFPA 704 placards. *Transportation identification, including DOT placards, type of road trailer, and type of rail car. Use WISER's protective distance mapping feature on your Android device to visualize the areas likely to be affected during the first 30 minutes after a substance is spilled released on a live map. The Department of Transportation's Emergency Response Guidebook serves as the source of WISER's protective distance data. (5/22/2014)
  • NLM updated Haz-Map with 481 new agents, including 23 agents causing occupational asthma. Fifteen new hazardous job tasks linked to jobs and industries were also added in this update. (2/10/2014)
  • A Hazardous Substances Data Bank record was created for 4-Methylcyclohexanemethanol, the chemical found in the January 2014 West Virginia Elk River chemical spill. (1/22/2014)


  • WISER for Windows 4.5 fully integrates Chemical Hazards Emergency Medical Management (CHEMM) content and updates the Emergency Response Guidebook (ERG) content to 2012. Full integration of CHEMM content includes: new hospital provider and preparedness planner profiles, along with a customized home screen for all WISER profiles, acute care guidelines for six known mass casualty agents/agent classes, the addition of a wealth of CHEMM reference material, and CHEMM Intelligent Syndromes Tool (CHEMM-IST), a new help identify tool designed to diagnose the type of chemical exposure after a mass casualty incident. ERG content is now updated to the 2012 release. This includes the full ERG 2012 tool. (11/22/2013)
  • The new web page, Typhoon Haiyan/Yolanda: Health-Related Information Resources, has resources that may be of value to international responders and response planners as well as to U.S. friends and family of people in the Philippines. (11/13/2013)
  • NLM activated the Emergency Access Initiative in support of medical efforts in the Philippines and surrounding areas following the devastating typhoon. EAI provides free access to books, journals and databases for people living and/or working in the affected area. (11/13/2013)
  • 452 new agents were added to Haz-Map bringing the total number of chemical and biological agents to 8689. Three new fields were also added to Haz-Map: Dangerous When Wet under TIH (Toxic Inhalation Hazard) in Exposure Assessment, NTP (National Toxicology Program) Carcinogen, and ACGIH (American Conference of Governmental Industrial Hygienists) Carcinogen (11/12/2013)


  • Tox Town Adds Methane to Chemical List. (12/4/2012)
  • Especially for Toxicologists was released and is a guide to NLM resources on environmental health, toxicology, and chemical information for toxicologists. (11/19/2012)
  • New resource page on laboratory safety released. The page has links to information for clinical, academic and school laboratories, including resources for handling chemical, biological and nanotechnology safely. Also included are links to regulations and policy, hazard analysis, MSDS, waste management, and preformulated TOXNET and PubMed searches. (11/19/2012)
  • Discovering the Connection: Your Environment, Your Health an afterschool science club curriculum for middle school students. Lessons and activities of the curriculum combine research on the Tox Town Web site with hands-on experiments and communication and social action activities. The objective is to introduce middle school students to environmental health issues in their everyday life, emphasizing the relevance of science to informed citizenship. The curriculum was developed as collaboration between NLM, University of Maryland College of Education, and an inter-disciplinary group of middle school teachers. It is based on National Science Education Standards and is grounded in problem-based learning approach that promotes in-depth understanding and critical thinking. (11/8/2012)
  • Tox Town Releases Drought Location Page.(10/25/2012)
  • The Disaster Information Management Research Center (DIMRC) released a Hurricane Sandy web page. It provides links to overviews, state specific sites, cleanup and recovery information, mental health information, multi-language resources, social media information, apps and widgets, and more. (10/06/2012)
  • NLM released GeneEd, a new educational resource. GeneEd is a collaboration with the National Human Genome Institute (NHGRI), teachers and experts in genetics and genetic counseling. It's a resource for students and teachers in grades 9 – 12 to explore topics such as Cell Biology, DNA, Genes, Chromosomes, Heredity/Inheritance Patterns, Epigenetics/Inheritance and the Environment, Genetic Conditions, Evolution, Biostatistics, Biotechnology, DNA Forensics, and Top Issues in Genetics. 3D images, illustrations and text from the NHRGI provide vivid imagery to reinforce genetic concepts. Text varies from easy-to-read to advanced reading levels. There are Teacher Resources and Labs and Experiments. (9/12/2012)
  • New page on Droughts and Health focuses primarily on human health effects of drought conditions as experienced in the United States. It is intended to grow as new materials become available on this topic. (8/13/2012)
  • The National Library of Medicine (NLM) announced a funding opportunity for small projects to improve access to disaster medicine and public health information for health care professionals, first responders and others that play a role in health-related disaster preparedness, response and recovery. NLM solicited proposals from partnerships that include at least one library and at least one non-library organization that has disaster-related responsibilities, such as health departments, public safety departments, emergency management departments, prehospital and emergency medical services, fire/rescue, or other local, regional, or state agencies with disaster health responsibilities; hospitals; faith-based and voluntary organizations active in disaster; and others. The deadline for proposals was Wednesday, August 8, 2012 at 2 pm ET. (7/10/2012)
  • Drug Information Portal made available for mobile devices. This mobile optimized web site covers over 32,000 drugs and provides descriptions, drug names, pharmaceutical categories, and structural diagrams. Each record also features information links to 19 other resources including NLM PubMed, NLM LactMed, and Drugs@FDA. The mobile version of a resource is used when available. (6/22/2012)
  • New web and mobile versions of Haz-Map released. The new Haz-Map design adapts to web browsers on desktop computers, laptops, tablets, as well as mobile browsers on smart phones, such as iPhones, Android and Blackberry phones. (6/22/2012)
  • TOXMAP now includes the 2010 Toxics Release Inventory data (TRI). (1/24/2012)


  • TOXMAP now provides information on the toxic chemicals used in hydraulic fracturing. Companies involved in hydraulic fracturing are not currently required to report to the US EPA Toxics Release Inventory Program and so are not represented in TOXMAP. However, TOXMAP provides information on many of the most toxic chemicals used. (12/12/2011)
  • Funeral Home Location added to Tox Town. Funeral home employees are exposed to a number of health and safety concerns. Visit the new page to learn about possible employee exposure to various chemicals, including formaldehyde and solvents, and bloodborne pathogens. (10/11/2011)
  • The new Enviro-Health Links page Developing and Using Medicines for Children provides links to resources that can help researchers, medical professionals and parents provide effective medicines and administer them safely. The links include information about pediatric drug development, clinical trials, and existing laws and regulations. (9/06/2011)
  • Chemical Hazards Emergency Medical Management (CHEMM) enables first responders and other healthcare providers and planners to plan for, respond to, recover from, and mitigate the effects of mass–casualty incidents involving accidental or terrorist chemical releases. CHEMM is a web-based resource that is downloadable in advance so that it is available during an event if the Internet is not accessible. It provides evidence-based information and guidance on a wide variety of topics, including quick chemical identification, acute patient care guidelines, and initial event activities. (7/13/2011)
  • Chemical Hazards Emergency Medical Management (CHEMM) enables first responders and other healthcare providers and planners to plan for, respond to, recover from, and mitigate the effects of mass–casualty incidents involving accidental or terrorist chemical releases. CHEMM is a web-based resource that is downloadable in advance so that it is available during an event if the Internet is not accessible. It provides evidence-based information and guidance on a wide variety of topics, including quick chemical identification, acute patient care guidelines, and initial event activities. (7/13/2011)
  • The Complementary and Alternative Medicines (CAM) update to LactMed added 19 of an expected 100 CAM products (cabbage, comfrey, lecithin, milk thistle, blessed thistle, stinging nettle, St. John's wort, garlic, fenugreek, blue cohosh, black cohosh, raspberry leaf, ginger, coenzyme Q10, borage, caraway, coriander, fennel, anise). These records focus on supplements that are frequently used by nursing mothers, including those claiming to stimulate lactation. Future products will include the most common supplements sold in the United States. A complete list of CAM records in the database can be found by using the search term “complementary therapies” in the main LactMed search box. (7/06/2011)
  • Embryo, a new app for the iPhone, iPod Touch and the iPad released - SIS has released Embryo, a new app for the iPhone, iPod Touch and the iPad. It is a collaboration between the National Library of Medicine (NLM), the Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD), the Virtual Human Embryo Project (Louisiana State University) and the National Museum of Health & Medicine's Human Developmental Anatomy Center. The Embryo app provides a collection of digital serial sections of early stage human embryos. Features include human fertilization videos, photo micrographs of early-stage embryo development, 2D and 3D digital images using visual stack dissections, and a pregnancy calculator. (05/17/2011)
  • Speaker slides and videocast of the March 29-30, 2011 Disaster Information Outreach Symposium available online
    • Day 1
    • Day 2
    • PDF version (PDF, 15 MB) of the PowerPoint slides for the "Roadmap to Disaster Health Information Resources and Tools" training class (04/25/2011)
  • ChemIDplus chemical structure images added to Hazardous Substances Data Bank (HSDB) records - ChemIDplus chemical structure images were added to Hazardous Substances Data Bank (HSDB) records. The chemical structures can be viewed in the HSDB record header with the chemical name and registry number. Users can save the chemical structure as a .png file using a right mouse click. This feature is not available via the HSDB document download feature These structures are also available in: Chemical Carcinogenesis Research Information System (CCRIS), Comparative Toxicogenomics Database (CTD)™, GENETOX, Integrated Risk Information System (IRIS) and International Toxicity Estimates for Risk (ITER). (04/07/2011)
  • LactMed App for iPhone, iPod touch, iPad and Android devices released - The LactMed App allows searching of the LactMed database from mobile devices. The database includes drug information on the possible effects on lactation and on breastfed infants, maternal and infant drug levels, and alternative drugs to consider. (06/22/2011)
  • Epigenomics - links to resources on epigenetics and epigenomics and the changes in the regulation of gene activity and expression that are not dependent on gene sequence (03/08/2011)
  • Water Pollution - links to web resources on drinking water, water pollution, bottled water, fluoridation, water contamination, disinfection byproducts, and Pharmaceuticals and Personal Care Products as Pollutants (PPCPs) (03/08/2011)
  • TOXMAP now includes 2009 Toxics Release Inventory data (TRI) 02/09/2011.


Cholera Resources added to the Health Resources for Haiti, Post-Earthquake page

They are in the first section titled "Earthquakes and Health". This page also includes extensive resources on many other topics relevant to post-disaster health care in Haiti, including resources in French, Spanish, and Haitian Creole. (10/28/2010)

The NLM Disaster Information Management Research Center (DIMRC) web pages redesigned

The DIMRC pages have been redesigned to enhance access to the many and diverse NLM resources useful for disaster and emergency readiness, response, and recovery. Emergency responders will find links to the WISER resource for hazardous materials incidents and the Radiation Emergency Medical Management site. (10/22/2010)

Environmental Health Student Portal Launched

The Environmental Health Student Portal introduces middle school students to environmental health science within the context of current middle school science curriculum standards. This newest edition to the family of NLM resources for students is free and does not require a subscription. The web site has links to government and other reviewed and selected sites and provides a safe and reliable environment for teachers and students to study the environment and its impact on health. The Environmental Health Student Portal allows students to conduct research, play games related to environmental health, locate science fair projects, and view videos. Teachers can use the site to locate links to relevant content and lesson plans from resources like the U.S. Environmental Protection Agency and the National Institute of Environmental Health Sciences. (10/22/2010)

Web pages refreshed

The Division of Specialized Information Services home page was refreshed in an effort to streamline information and to make the Division’s resources easier to access. In addition to some new banners for some secondary pages, the home page now includes the same “Search Our Web Site” feature included on the Toxicology and Environmental Health (TEHIP) page. Please note that this entry point searches the SIS web site. TOXNET searches should be initiated on the TOXNET home page or via the “Search TOXNET” feature of the TEHIP page. (10/22/2010)

Enviro-Health Link page on Hexavalent Chromium and Other Chromium Compounds

Hexavalent Chromium and Other Chromium Compounds provides links to materials on this drinking water contaminant and its effects on human health. Also included are links to regulations and policy, and TOXNET and PubMed searches. (12/23/2010)

Tox Town added 6 chemical pages that are also available in Spanish

Polycyclic Aromatic Hydrocarbons (PAHs), Hidrocarburos aromáticos policíclicos (HAP), Polybrominated Diphenyl Ethers (PBDEs), Éteres difenílicos polibromados (PBDE), Polyvinyl Chloride (PVC), Cloruro de polivinilo (PVC), Perchlorate, Perclorato, Methanol, Metanol, Ethylene Oxide, and Óxido de etileno. (09/13/2010)

Guide to web sites on Bed Bugs and Pesticides

A section on the use of pesticides to control bed bugs has been added to the Enviro-Health Links page on Pesticide Exposure. (09/09/2010)

Animals in Disasters

Animals in Disasters provides links to information on preparing for disasters if you have animals. Included are links to sites on rescue, animal handling for emergency responders, how to care for livestock during emergencies, carcass disposal, the Pets Evacuation and Transportation Standards Act of 2006, and Spanish language materials. (9/08/2010)

AIDSinfo Launches Mobile Site

AIDSinfo now offers a mobile site for accessing its resources and information on-the-go. The new site optimizes many of the main site’s features for phones and other mobile devices. JavaScript must be enabled on your device for the mobile site to function properly. (09/20/2010)

New records for Corexit 9500, Corexit 9527, and Crude Oil added to the Hazardous Substances Data Bank (HSDB)

In response to information inquiries following the 2010 Deep Water Horizon oil spill, the HSDB development team along with members of the Scientific Review Panel (SRP) began compiling and reviewing data to create records for crude oil, Corexit 9500 and Corexit 9527. (08/18/2010)

WISER (Wireless Information System for Emergency Responders) for BlackBerry Released

The National Library of Medicine (NLM) WISER (Wireless Information System for Emergency Responders) has released WISER for BlackBerry. This release features quick online access to WISER's full database of chemical, biological, and radiological substances and easy access to WISER's help identify capability and full suite of tools. (07/28/2010)

Household Products Database Updated

The Household Products Database now includes 10,000 brand name products, 3,214 ingredients, and 395 manufacturers. In addition, 4,111 products are now linked to the complete Material Safety Data Sheet (MSDS). (07/20/2010)

FDA Substance Registration System Database search

This database provides access to the FDA Unique Ingredient Identifier (UNII) assigned to substances by the FDA Substance Registration System. The UNII is an essential element required for the listing of substances in the FDA Structured Product Labeling (SPL). The Division of Specialized Information Services (SIS) of the National Library of Medicine (NLM) and the FDA collaborated to make access to this code easier. Users entering a substance name or a UNII will be directed to the FDA record. Spell checking and autosuggest are available for each query. If no UNII is available for a substance, the user is referred to the FDA to request one. Links to the NLM ChemIDplus and the Drug Information Portal are provided for most drugs. The database is updated weekly with data provided by FDA. (07/16/2010)

Resources for Disaster Planning and Response Presentation

The Resources for Disaster Planning and Response presentation given at the 2010 Medical Library Association meeting in Washington, DC is available online. (07/06/2010)

Toxicology & Environmental Health Update

The Toxicology & Environmental Health Update given at the 2010 Medical Library Association meeting in Washington, DC is now available online. (07/02/2010)

Crude Oil Spills and Human Health

A page of links to information on Crude Oil Spills and Human Health is now available from the National Library of Medicine. The page provides links to information on how the United States responds to oil spills, state agencies in the Gulf region that respond to spills, occupational hazards for professionals and volunteers assisting with clean-up, seafood safety and more. A widget that links to the page was created. (04/29/2010)

Tox Town releases a Bisphenol A (BPA) page

Tox Town releases a Bisphenol A (BPA) page. The summary is also available in Spanish at Bisfenol A (3/24/2010).

Environmental Health and Toxicology page redesigned.

One of the goals of the update was to make the site more approachable and understandable with the use of images, descriptions, and other tools. The site can now be navigated with less scrolling. (03/23/2010)

Tox Town releases a Nanoparticles page

The nanoparticles page provides a brief summary of nanotechnology and has links to additional resources. The summary can also be found in Spanish at Nanopartículas. (02/03/2010)

TOXMAP now includes TRI 2008 data and results that can be displayed in Google

TOXMAP now includes 2008 Toxics Release Inventory data (TRI).

Other TOXMAP updates include:

  • the ability to view search results in Google Maps and in Google Earth
  • a new look for the TOXMAP FAQ

New Enviro-Health Link page on Imported (Chinese) Drywall

In the past year homeowners have reported problems with drywall produced in China. This new web bibliography links to resources about the research into and guides to dealing with imported drywall. (1/26/2010)

New Enviro-Health Link page on Nanotechnology

Nanotechnology provides links to materials on nanotechnology uses and environmental concerns. Also included are links to databases, maps, regulations and policy, and TOXNET and PubMed searches. (01/26/2010)

Haiti Earthquake Resource Page

The Haiti Earthquake page lists web pages about the Haiti earthquake situation from both government agencies and non-governmental organizations (NGOs). There is also a section on Haitian Creole and French-language materials. Links to background information on earthquakes and subsequent health issues, such as public health assessments, emergency surgical care, and management of dead bodies, are included. (01/20/2010)

265 agents added to Haz-Map

Agents added to Haz-Map include 60 assorted metal compounds, 100 rare earth metals, 10 uranium compounds, 16 metallic perchlorate compounds, 9 thiols, 4 sulfites, 20 nitriles, 6 glycol ethers, 4 fluorides, 7 aldehydes, and 5 acid anhydrides. (01/06/2010)



ToxLearn is now available

ToxLearn is a multi-module online learning tool that provides an introduction to toxicology. It can be used as an ancillary curriculum to a first-level undergraduate toxicology course, and can provide users of NLM toxicology databases with a working knowledge of basic toxicology principles. “Introduction to Toxicology and Dose-Response” is the first module. Additional units will be made available as they are completed.

ToxLearn is an update of the Toxicology Tutor (Tox Tutor). Both Tox Tutor and ToxLearn will be available while ToxLearn is finished. (12/7/2009)

Update for WISER for Windows 4.3 now available

An update for WISER for Windows 4.3 is now available. This update corrects a recently reported protective distance mapping issue. Highlights of this version also include: Improved display of WISER for Windows on low resolution displays and Usability improvements to the included ERG 2008 tool. (11/16/2009)

Radiation Event Medical Management System (REMM) wins Web Health Award

The Radiation Event Medical Management System (REMM) won a bronze award in the Spring/Summer 2009 Web Health Awards in the category of web sites produced by the government for health professionals. The Web Health Awards is a program that recognizes the best Web-based health-related content for consumers and professionals. It is organized by the Health Information Resource Center (HIRC) , a national clearinghouse for consumer health information programs and materials. Entries in the Spring/Summer 2009 Web Health Awards Program were evaluated for content and creativity. (11/12/2009)

Nanomaterials added to the Hazardous Substances Data Bank (HSDB)

Seven HSDB nanomaterial records were added to HSDB: 1) Carbon nanotubes, 2) Fullerenes, 3) Silver nanoparticles, 4) Iron nanoparticles, 5) Titanium oxide nanoparticles, 6) Zinc oxide nanoparticles, and 7) Cerium oxide nanoparticles. Information on hollow, spherical or ellipsoidal carbon nanostructures is found in the fullerenes record. The carbon nanotubes record contains information on tubular or lattice materials. The fields of nanoparticles and nanostructures, as well as associated nomenclature, are continually evolving. Information and/or records will be added as data become available. (10/23/2009)

WISER 4.3 is now available

  • WISER for Windows has a new and improved user interface.
    • The Known Substance and Help Identify Unknown Chemical result lists are always visible, reducing unnecessary navigation
    • An enhanced data menu maintains the context of the previous selection and can be kept open for quick navigation.
    • Substances can now be compared directly using a synchronized data menu.
    • Substance tabs and new auto-arrange features allow the viewing of multiple substances.
  • All WISER platforms include data updates based on the latest Hazardous Substances Data Bank (HSDB), Center for Infectious Disease Research and Policy (CIDRAP) for biological agents, and U.S. Environmental Protection Agency Acute Exposure Guideline Levels (EPA AEGLs) content.
  • Miscellaneous usability improvements and fixes. (8/31/2009)

TOXMAP Updates

TOXMAP now has updated mortality data and a new look for its News. Other TOXMAP updates include the ability to enter map descriptions to saved search results and a TOXMAP widget and toolbar

The TOXMAP widget allows you or your users to launch a TOXMAP search from your blog, wiki, or Web page. Enter a ZIP code into the widget to see a map of TRI facilities and Superfund NPL sites, or click "More info" to go to the TOXMAP home page.

The TOXMAP Toolbar lets you search TRI releases, Superfund National Priorities List (NPL) sites by contaminant, or TRI facilities and Superfund NPL sites by ZIP code-- all from your browser search box. (7/8/2009)

ToxMystery and Toxie the Cat come to your desktop with 3 wallpaper designs

A series of three wallpaper designs are now available for fans of ToxMystery. The cheery designs show Toxie the Cat in his Earth Day T-Shirt and come in three colors. You can download the wallpaper from (7/24/2009).

TOXMAP: Now Includes TRI 2007

TOXMAP now includes the 2007 EPA Toxics Release Inventory data (TRI). In addition, TOXMAP now offers the ability to save one's search results, the ability to zoom to U.S. Indian reservations, and county and Congressional district boundaries that can be toggled on/off. (3/26/2009)

Improvements to the Dietary Supplements Labels Database

The Dietary Supplements Labels Database now includes several interface improvements, more products, and an auto-complete (search) feature. Other recent additions/changes include:

  • Search box on every page
  • Age/gender categories under “Products”
  • Glossary page with A-Z anchor links
  • Updated FDA Recalls, FDA MedWatch and FTC Actions
  • More products (3000)
  • New “Help” page. (02/03/09)

New Enviro-Health Link page on Public Health Preparedness for Mass Gatherings

Links to information on the public health aspects of planning for all kinds of mass gatherings. The page includes a search of PubMed for medical journal article citations as well as documents from government and other sources. (1/13/09)

New Enviro-Health Link page on TVA Kingston Fossil Plant Coal Ash Spill, December 2008

This new web bibliography brings together resources on the December 2008 Tennessee Valley Authority Kingston Fossil Plant Fly Ash Release, including the potential effects of fly ash exposure on human health. (1/5/2009)



Radiation Event Medical Management (REMM) can now be downloaded to mobile devices

The Radiation Event Medical Management System (REMM) can now be downloaded to mobile devices (Blackberry, Windows Mobile, and Palm) with selected key files from the full online version. (12/09/2008)

New version of the Drug Information Portal released

The Drug Information Portal now covers over 16,000 drugs. Other recent changes include:

  • Direct searching of drug categories, which are derived from the Medical Subject Heading (MeSH®) Pharmacological Action field
  • Name and category suggestions, to eliminate common spelling errors
  • Phrase parser that assists users in finding drug names within phrases
  • The addition of the MeSH notes, when available, to spell checker results to make selection of a possible answer easier
  • Searches retrieving multiple results now sorted by frequency of citation in PubMed®, from highest to lowest. This tends to show the most commonly used drugs first. (10/31/2008)

Haz-Map has been updated.

The latest Haz-Map update includes 180 new chemical profiles, submitted by the United States Department of Labor. (10/6/2008)

Household Products Database Updated

The Household Products Database was recently updated and now contains:

  • 8152 products
  • 375 manufacturers
  • 1634 products link to complete MSDS (10/1/2008)

Improved user interface, updated mortality data, and addition of hospital locations in TOXMAP

TOXMAP now includes several interface improvements, updated mortality data (2001-2005), and names and locations of hospitals when the map is zoomed to the most detailed level.

Other recent changes include

  • Ability to view TRI facilities reporting releases in a particular TRI year, similar to TRI chemical releases
  • Inclusion of links to TRI state fact sheets from EPA
  • Ability to zoom to US national parks via “Zoom to a Place”
  • Ability to toggle on and off the “auto-zoom” behavior in the main Search page
  • PubMed RSS feed
  • Section 508 compliance improvements (10/1/2008)

Illustrated glossary and a Spanish home page for ToxMystery

ToxMystery, the National Library of Medicine's interactive learning site for kids has added a Spanish home page. This URL lets users start the game in Spanish without clicking on the language tab from the English site. Gamers can still move between Spanish and English as Toxie the Cat helps them explore the site's “house of hazards.” An illustrated glossary of the words used in ToxMystery was also added to the Teacher's Resource page. The glossary is available in Spanish from the “Para maestros” section. (7/14/2008)

New Enviro-Health Link page on Disaster Recovery and Environmental Health

This new web bibliography brings together resources on recovering from a disaster whether natural or man-made. Among the resources are guides for state and local officials, links to state emergency management offices, information for emergency responders, guidelines for workers involved in environmental cleanup and handling hazardous chemicals. (6/11/2008)

NLM Aids Federal Effort to Distribute Revised Hazmat Guidebooks to Emergency First Responders

The U.S. Department of Transportation (DOT) announced that it is granting emergency responders electronic access to the Emergency Response Guidebook 2008 (ERG2008), through laptops and personal digital assistants (PDAs), under a joint effort between DOT's Pipeline and Hazardous Materials Safety Administration and the National Library of Medicine (NLM. This new hazmat safety guide for police, fire and other emergency response organizations is designed to aid emergency response personnel who may be the first to arrive at the scene of a transportation incident involving hazardous materials. The NLM-developed software application and NLM's Wireless Information System for Emergency Responders (WISER) software are stand-alone applications for Pocket PCs, PDAs, and Windows-based laptop computers. This joint effort keeps pace with the advance of portable personal technology and fulfills the request of a number of emergency responders for an electronic-based ERG. DOT is also distributing nearly 1.75 million print copies of the ERG. (5/07/2008)

New Enviro-Health Link page on Mercury and Human Health

Mercury's effects on health are a common concern. This new web bibliography, Mercury and Human Health, includes links to sites about mercury reduction, occupational exposure, compact fluorescent light bulbs, mercury in health care, and regulations and state legislation. (4/17/08)

TRI 2006 Released

The new TRI 2006 release contains 87,870 records. TRI87-2006 now has 1,738,086 records. There were two changes to reporting requirements for the 2006 data. Facilities were required to submit appropriate North American Industry Classification System (NAICS) codes rather than the Standard Industrial Classification (SIC) codes previously used. To do trends analysis, EPA assigned NAICS codes to prior years' data, so now both SIC codes and NAICS codes are searchable on TOXNET. EPA also expanded Form A eligibility to include PBT chemicals in 2006. (4/17/08)

TOXMAP: Now Includes TRI 2006, Updated Health Data

TOXMAP now includes the 2006 Toxics Release Inventory data (TRI). (4/17/08)

Disaster Information Management Research Center (DIMRC) Launched

The DIMRC web site provides access to quality disaster health information at all stages of preparedness, response, mitigation, and recovery. Initially, the site will focus on NLM and NLM-supported resources and activities. It will then expand to include other sources of authoritative disaster health information.

DIMRC collects, organizes, and disseminates health information for natural, accidental, or deliberate disasters.  The Center is committed to providing this information as part of the federal effort to help prepare for, respond to, recover from, and mitigate the adverse health effects of disasters. It will work with federal, state, and local government, private organizations, and local communities. (4/03/2008)

Drug Information Portal Released

The NLM Drug Information Portal gives the public, healthcare professionals, and researchers a gateway to current, accurate and understandable drug information from the National Library of Medicine and other key government agencies.

More than 15,000 drug records are available for searching. The search interface is straightforward, requiring only a drug name as a search term, and successful searching is enhanced by the assistance of a spellchecker. The Drug Information Portal offers a varied selection of resources and focused topics in medicine and drug-related information, with links to individual resources with potential drug information and summaries tailored to various audiences. General drug categories from MeSH are also included in the Drug Portal records. (2/13/2008)

TOXMAP: New Health Data, Roads

TOXMAP now contains updated cancer and other mortality data. TOXMAP also now shows more detailed roads at a variety of map scales. (Roads and other reference data can be hidden from maps via the “Other Data” subtab.)

Other recent changes include:

  • Facility details include latitude/longitude and links to Google Maps
  • Redesigned Search and Set Region pages
  • Added “go to” page number for search results
  • Added aggregate release data values in downloadable TRI facility data
  • Added HTML Site Map; Added Income 2003 demographic layer
  • Added ability to link directly to site details (all map types). (2/12/08)

Special Populations: Emergency and Disaster Preparedness

A new Web page, Special Populations: Emergency and Disaster Preparedness, is available on the Specialized Information Services (SIS) Web site. The page provides relevant information regarding the needs of special population groups in planning and preparation before, and response and recovery after disasters and emergencies. It was created after natural disasters such as hurricanes and wildfires, diseases such as SARS and West Nile Virus, and the terrorist attacks of 9/11 illustrated the need to ensure widespread access to knowledge about populations with unique needs in these emergencies. The population groups addressed include the mentally and physically disabled, senior citizens, minority, ethnic and language groups, women and children and others whose situations require different or specialized measures be taken in disaster preparedness and recovery. Also includes links to information in languages other than English. (2/2/2008)

Carcinogenic Potency Database (CPDB)

CPDB, the Carcinogenic Potency Database, was developed by the Carcinogenic Potency Project at the University of California, Berkeley, and by the Lawrence Berkeley National Laboratory. It reports analyses of animal cancer tests on 1547 chemicals. Results for each chemical are now searchable via TOXNET.

CPDB includes 6540 chronic, long-term animal cancer tests (both positive and negative for carcinogenicity) from the general published literature as well as from the National Cancer Institute and the National Toxicology Program. Such tests are used in support of cancer risk assessments for humans. Information that is important in the interpretation of bioassays is reported in CPDB for each experiment.

Users can search for results on each chemical in TOXNET via chemical name or name fragment, or by Chemical Abstracts Service Registry Number (RN). Results include a summary for each sex-species tested, including carcinogenicity, target organs, and carcinogenic potency values. Detailed results from each experiment on the particular chemical are given in a plot format suitable for screen viewing. Chemical structure, InChI, and SMILES codes are reported. (1/10/08)



New Enviro-Health Link on the California Wildfires released

The California Wildfires Enviro-Health Link includes information on the health effects from fires and exposure to smoke; links to air quality resources, environmental clean-up following fires, and animals in disasters. In addition, resources for emergency responders and information in Spanish are also included. Searches of NLM databases, such as MedlinePlus, PubMed, TOXLINE, Tox Town, Haz-Map and TOXMAP are provided for additional health information. This web page is designed to help the emergency responders, health care providers, public health workers, and the general public find authoritative and timely information about key health concerns from wildfires. (10/24/07)

Dietary Supplements Labels Database released

The National Library of Medicine has released a new resource focused on dietary supplements. The Dietary Supplements Labels Database includes information from the labels of over 2,000 brands of dietary supplements in the marketplace, including vitamins, minerals, herbs or other botanicals, amino acids, and other specialty supplements.

The database is designed to help both the general public and health care providers find information about ingredients in brand-name products, including name, form, active and inactive ingredients, amount of active ingredient/unit, manufacturer/distributor information, suggested dose, label claims, warnings, percentage of daily value, and further label information.

Links to other NLM resources, such as MedlinePlus and PubMed, are provided for additional health information. In addition, links to related Fact Sheets from the U.S. Food and Drug Administration (FDA), Office of Dietary Supplements (ODS), National Center for Complementary and Alternative Medicine (NCCAM), and the National Cancer Institute (NCI) are also available. (10/24/07)

WISER for Smartphone is now available

WISER is now supported on Windows Mobile Smartphones, which consist of Windows Mobile devices that do not have a touch screen (do not use a stylus). (Note that Windows Mobile phones with a touch screen are already supported by WISER for Pocket PC.) The new WISER for Smartphone release is functionally equivalent to ourPocket PC version of WISER, and can be downloaded from

Please be sure to read the system requirements and installation instructions that are in the README, which is linked to on the download page and included in the installation. Some users may run into storage space limitations when installing WISER for Smartphone; procedures for resolving such issues are included in the README. (10/22/07)

Toxie the Cat can now speak Spanish/ Toxie the Cat ahora habla español

Toxie, the ToxMystery guide cat, has gone back to school and can now speak Spanish. By selecting the Espanol or English tab on the upper right of the home page,ToxMystery gamers can move between Spanish and English as they explore the site's "house of hazards."

ToxMystery en español's "Para los padres" (For Parents) page gives parents more detailed information about potential household hazards. The teachers' "Para maestro"" page has lesson plans and downloadable classroom activity pages in Spanish. ToxMystery can be used in science and health classes.

Come play with Toxie and see if you can find the hazards in English and en español! (10/01/07)

New version of TOXMAP Released

This version includes:

  • More search options: Users can now search TOXMAP by Chemical Abstracts Service/Registry Number (CAS/RN), Toxics Release Inventory (TRI) facility name/ID, release medium, release year ranges, release amount, Superfund (NPL) site name/ID, and Hazard Ranking System (HRS) score.
  • Geographic regions: Users can create their own geographic region, or select a pre-defined region from a menu. Setting a geographic region limits search results to those inside the specified region. Regions can be saved for future access.
  • Regional TRI summary tables: Users can view summary (aggregate) TRI release amounts for their geographic region.
  • Updated and expanded glossary and FAQs. (8/30/07)

New Enviro-Health Link on the Hazards of Arts and Crafts Materials

Keeping the Artist Safe: Hazards of Arts and Crafts Materials is the latest addition to the National Library of Medicine's (NLM) Enviro-Health Links web bibliographies. Artists, craftspeople, and hobbyists use potentially hazardous substances. Learn more about the hazards and how to protect yourself from unnecessary exposures. (7/31/07)

Vera Hudson

Vera Hudson, long time staff member of NLM’s Specialized Information Services Division, died June 20, 2007. Ms. Hudson had worked at SIS for 24 years. As an information specialist, she helped to define and evaluate the effects of toxic chemicals. From 1975 to 1983, she worked for the National Institute for Occupational Safety and Health and focused on the effects of occupational chemical exposure. She also worked on the development and maintenance of the institute's registry of toxic effects of chemical substances. She was a 1958 biology graduate of the American University of Beirut and received a master's degree in physiology from the University of Kansas at Lawrence in 1960. If you need to contact someone about one of Ms. Hudson’s projects, send email to (6/28/07)

Version 3.0 of WISER released

Version 3.0 includes:

  • Radiological support, including data for 20 isotope substances and a general "ionizing radiation" substance, and tools/reference materials for radiological incidents
  • An ERG 2004 Tool, comprising the complete ERG with powerful search capabilities
  • Improved, more powerful search capability of the substance list, including wildcarding
  • Substance categories support: view all substances, just chemicals, just radioisotopes, or filter by substance categories such as the classes/divisions of the Hazard Classification System. Identify unknown substances, and group the results list, by substance categories
  • 9 new user-requested chemical substances, and incorporation of the latest Hazardous Substance Data Bank updates
  • Protective Distance substance data menu option now includes the "Initial Isolation and Protective Action Distances" data from the ERG 2004 (5/29/07)

New Look for ChemIDplus

A colorful new banner serves to prominently highlight useful links to site information in ChemIDplus Lite and Advanced and offers one-click access to NLM and SIS homepages. The News link offers information regarding the latest updates and enhancements for both versions of ChemIDplus. An additional new feature is the Structure Salt/Parent Search button, which gives quick access to salts and hydrates of a parent record.

InChI and SMILES now available

Structure descriptors have been added to ChemIDplus Lite and Advanced. The structure descriptors include the InChI and SMILES notation. Recently developed by the IUPAC, InChI is the acronym for International Chemical Identifier. Likewise, SMILES is the acronym for Simple Molecular Input Line Entry System. Both structure descriptors can be accessed from the search results page. By selecting either the Full Record or the Structure button, this information can be viewed directly below the structure image. InChI and SMILES notation appear in over 270,000 records.

New Locators

New database locators offer another dimension to information resources provided by ChemIDplus. Recently added ChemIDplus locators include:

  • DailyMed - Vehicle for access to the labels as well as to other sources and types of information about medications
  • DrugDigest - A noncommercial, evidence-based, consumer health and drug information site.
  • Drugs@FDA - A website where you can search for official information about United States Food and Drug Administration (FDA) approved brand name and generic drugs.
  • EPA HPVIS - EPA’s High Production Volume Information System (HPVIS) provides access to select health and environmental effect information on chemicals that are manufactured in exceptionally large amounts.
  • EPA PPIS - The Environmental Protection Agency (EPA), Pesticide Product Information System (PPIS) contains information concerning all pesticide products registered in the United States.
  • LactMed - A database of drugs and other chemicals to which breastfeeding mothers may be exposed
  • PubChem - Provides information on the biological activities of small molecules.
  • - Official information and services from the U.S. government related to your ChemIDplus search
  • WebWISER - A Wireless Information System for Emergency Responders (WISER) designed to assist first responders in hazardous material incidents. Originally developed for the Palm PDA based on Hazardous Substance Data Bank (HSDB) data, WebWISER provides WISER information in a database on the web. (4/23/2007)

MedlinePlus Locator for ChemIDplus records

The MedlinePlus locator now has two options, MedlinePlusAll and MedlinePlusDrug. MedlinePlusAll links to all information related to the ChemIDplus record available in MedlinePlus. MedlinePlusDrug links to the specific drug information related to the ChemIDplus record. (March 2007)


DIRLINE (Directory of Health Organizations) now offers an A to Z list of 8,500+ organizations concerned with health and biomedicine. (3/16/07)

LactMed Updated

The National Library of Medicine's Drugs and Lactation Database (LactMed) has added 51 substances, including 14 topical antibacterial and antifungal agents, 13 X-ray and 8 MRI contrast agents, 8 acne/skin care agents, and 8 other drugs. 36 records have been updated. More specific information about this update can be found at the LactMed 3/2007 listing. (3/27/07)

TRI2005 Released

TRI2005 was released to the public on TOXNET on March 23, 2007. The new release contains 89,325 records. (3/26/07)

Haz-Map Updated

Haz-Map has been updated. 226 new agents in the categories of metals, solvents, pesticides, mineral dusts, toxic gases and vapors, plastics and rubber, nitrogen compounds, and other compounds were added. (3/26/07)

HHS Launches New Online Portal for Medical Responses to Radiation Emergencies

On March 8 HHS Secretary Mike Leavitt announced the Department of Health and Human Services had developed its first comprehensive web portal to assist health care providers, primarily physicians, who may have to provide medical care during a radiation mass casualty incident. The new portal, Radiation Event Medical Management (REMM), provides easy to follow algorithms for diagnosis and management of radiation contamination and exposure, guidance for the use of radiation countermeasures, and a variety of other features to facilitate medical responses.

Critical information is presented in a format that will quickly and efficiently orient and guide health care providers during a potential mass casualty radiation event. Federal, state and local medical response teams will be able to download REMM files to laptop computers so the documents will be available without Internet access. Users can also register for automatic e-mail updates whenever key material is changed or added to the REMM toolkit. (3/9/07)

New Look for TOXNET Search Results Page

The Search All TOXNET Databases Results page has a new look. References from TOXLINE (Toxicology Literature Online) and DART (Developmental and Reproductive Toxicology) are displayed first, followed by records from the other TOXNET databases (Chemical, Toxicological, and Environmental Health data). For each database, the database abbreviation, full name, and number of records found are displayed. Click on any database to go to its results page. (2/20/07)

From Ship to Shore…

Tox Town’s New Port Scene Delivers the Goods on Coastal Environmental Health What do longshoremen, sunbathers, ship crews, and shrimp lovers have in common? Whether they live on the coast, work in a maritime industry or play on the beach, they can find information about the environment and how it might affect their health at Tox Town’s new Port neighborhood. This imaginary port illustrates drinking water and air quality concerns along with wastewater treatment, shellfish safety, work hazards, sun and surf safety, aquaculture and many other topics. The port also highlights possible locations and descriptions of 26 hazardous chemicals. (1/25/07)



WISER (2.3) is now available for download

  • Data updated to reflect the latest content of NLM’s Hazardous Substance Data Bank (HSDB)
  • New data item: Ionization Potential (see Physical Properties data menu)
  • New data item: EPA’s Acute Exposure Guideline Levels (AEGL) (see Medical data menu)
  • New substances requested by users: Acrylic Acid and Ethyl Methyl Ether
  • Improved presentation of ERG 2004 guide pages (not yet on Palm OS)
  • Updated and improved NFPA 704 data
  • Improved NFPA 704 presentation, including placard displays (not yet on Palm OS)
  • Searching and grouping by NFPA 704 hazards in “Help Identify” is now available on the Pocket PC (as well as WISER for Windows and WebWISER)
  • Support for non-standard Pocket PC screen sizes and orientations
  • Event Tracking (logging) added to WISER for Windows and Pocket PC (see the User’s Guide) (12/01/06)

TOXMAP has improved location data

The EPA recently released updated and more accurate TRI location data from its Facility Registry System (FRS). TOXMAP has incorporated these changes, which correct many TRI location inaccuracies in the FRS. Such corrections will continue to be incorporated into TOXMAP as they become available. (11/17/06)

HSDB Ionizing Radiation Series

A record for ionizing radiation and a series of specific radionuclide records have been added to NLM's Hazardous Substances Data Bank/HSDB. (11/02/06)

ToxMystery: A new interactive learning site for young kids

ToxMystery is the National Library of Medicine's new, interactive learning site for 7-10 year old kids. It provides a fun, game-like experience while introducing potential environmental health hazards sometimes found in the home. (10/03/06)

New Enviro-Health Link on Dietary Supplements

Dietary Supplements is the latest addition to the National Library of Medicine's (NLM) Enviro-Health Links. The page links to information on dietary supplements plus vitamins and minerals, as well as herbs, botanicals and other substances. It covers research, use, databases, and law and policy. (9/25/06)

New look for TOXMAP

TOXMAP's maps now have a more accurate appearance. For more information on how maps are drawn, see our FAQ

Other new TOXMAP features include:

  • TRI releases summary table for each TRI facility showing all years and chemicals in table format;
  • Larger default maps (with the option for small maps);
  • Enhanced homepage map;
  • Auto-completion of chemical names in text entry fields (like Quick Search);
  • A "For Teachers" page that includes a downloadable sample assignment. (8/9/2006)

New version of the National Library of Medicine's (NLM) TOXLINE

A new version of the National Library of Medicine's (NLM) TOXLINE will be released on Tuesday, July 18, 2006. Search results from the two parts of TOXLINE will be now be merged. This will allow all results to be relevancy ranked in the same way, with results displayed in only one window. A similar merged interface will be provided for the Developmental and Reproductive Toxicology/Environmental Teratology Information Center (DART®/ETIC) database in the Fall.

Citations from PubMed will directly link back to PubMed for convenience in using their related records, LinkOut, and document ordering functions. (7/18/2006)

WISER version 2.2 is now available for download The highlights of this release include:

  • Updated data that continues to fill data holes and provides miscellaneous improvements.
  • 15 new substances, including all that have been suggested by users.
  • The Help Identify feature of WISER for Windows now allows searching by NFPA 704 placard.
    This feature will also be coming soon in the PDA and WebWISER applications, and will include
    more comprehensive data. (4/27/2006)

TRI2004 Released

TRI2004 was released to the public on TOXNET on April 12, 2006. The new release contains 89,653 records. (4/12/06)

LactMed: A New Database on Drugs and Lactation from the National Library of Medicine

LactMed, a free online database with information on drugs and lactation, is one of the newest additions to the National Library of Medicine’s (NLM) TOXNET system, a Web-based collection of resources covering toxicology, chemical safety, and environmental health. Geared to the healthcare practitioner and nursing mother, LactMed contains over 450 drug records. It includes information such as maternal levels in breast milk, infant levels in blood, potential effects in breastfeeding infants and on lactation itself, the American Academy of Pediatrics category indicating the level of compatibility of the drug with breastfeeding, and alternate drugs to consider. References are included, as is nomenclature information, such as the drug’s Chemical Abstract Service’s (CAS) Registry number and its broad drug class.

LactMed was developed by pharmacist who is an expert in this subject area. Three other recognized authorities serve as the database’s scientific review panel. Ancillary resources, such as a glossary of terms related to drugs and lactation, and breastfeeding links are also offered. LactMed can be searched together with TOXNET’s other databases in a multi-database environment, to obtain other relevant information about drugs. As a work in progress, LactMed will continue to expand with additional drugs and be enhanced with other substances, such as industrial chemicals and radiation. (4/11/06)

TOXMAP adds new chemical and health data

New chemical and health-related data has been added to the interactive mapping site, TOXMAP.

TOXMAP helps users explore the geographic distribution of certain chemical releases, their relative amounts, and their trends over time. This release data comes from industrial facilities around the United States, as reported annually to the Environmental Protection Agency (EPA).

Now, users can also use TOXMAP to find information about Environmental Protection Agency (EPA) Superfund sites and substances. The Superfund program is part of a federal government effort to clean up land in the United States that has been contaminated by hazardous waste and identified by the EPA as a candidate for cleanup because it poses a risk to human health and/or to the environment.

TOXMAP has also added mortality data from the Centers for Disease Control and Prevention (CDC) and the National Cancer Institute (NCI), as well as age and gender data from the US Census, and income data from the Bureau of Economic Analysis.

More information about TOXMAP can be found at the fact sheet. (03/1/2006)

New structure searching features in ChemIDplus

ChemIDplus has added new structure searching features to its Advanced search page recently. The “Exact (parent only)” feature searches for exactly what is drawn or transferred to the structure box.

The new features called “Flex” and “Flexplus” allow searching for records which contain a parent structure plus additional components. These components may be salts, hydrates, or mixtures with other chemicals. The new features will take the input structure and find records where it is mixed with other compounds. An example would be the drug named “Aleve” which is the soluble sodium salt of naproxen. If the structure of “Aleve” is transferred by the appropriate button to the structure box, The Exact search retrieves one record. If the Flex search is chosen and searched, the system will retrieve the parent naproxen record, as well as seven other salts and mixtures of naproxen for a total of nine records. Most of these would be of interest in a search for data on the effectiveness or toxicology of “Aleve”.

The Flexplus feature also retrieves nine records in this case, however since it is more generalized to allow different stereochemistry and bonding, it may sometimes retrieve more records than a Flex search, however some may not have the same characteristics as the parent.

These new features are described in more detail in the ChemIDplus Advanced Help. (02/14/06)



Lead and Human Health added to Enviro-Health Links

A new web page, Lead and Human Health, that addresses the relationship between lead and human health has been added to the National Library of Medicine's (NLM) Enviro-Health Links. The page contains links to selected web sites on exposure, treatment, and prevention of lead poisoning. (12/15/05)

WebWISER makes WISER available on the Internet

A web version of the National Library of Medicine's WISER is now available. WebWISER provides the WISER functionality via the Internet, without downloading of software or data to the desktop. It has a consistent look and feel of the WISER for Windows desktops/laptops and PDAs. WebWISER supports web browsers for both PCs and PDAs, including BlackBerry.

Visit the general WISER website for:

  • Free downloads of WISER for PDAs and Window PC platforms
  • A WISER tutorial, and
  • Links to other useful information for emergency responders (12/06/05)

ToxSeek Released

ToxSeek is a meta-search and clustering engine that enables simultaneous searching of many different information resources on the World Wide Web. ToxSeek uses natural language processing and artificial intelligence to retrieve, integrate, rank, and present search results as coherent and dynamic sets. ToxSeek’s results “clustering” feature helps users to more easily identify particular concepts. These “clusters” are created from what is retrieved in the original query, and can be useful in uncovering a specific concept or focus for more in-depth searching.

ToxSeek searches across a wide range of authoritative sources including:

  • All TOXNET databases
  • Additional selected resources from the National Library of Medicine (NLM), including PubMed
  • Resources from other NIH institutes, toxicology/environmental health information from other United States government agencies
  • Selected international resources, such as the World Health Organization (WHO)
  • Resources from professional societies and scientific organizations (11/14/05)

WISER Release 2.1

The 2.1 release of WISER has updated data, more refined search results and a new print capability from the Windows version. Available for the Palm, Pocket PC and Windows desktop/laptops.

Go to the WISER home page to download the new versions. (9/29/2005)

New Design for ALTBIB - Bibliography on Alternatives to the Use of Live Vertebrates in Biomedical Research and Testing

Obtaining relevant information on animal alternatives from MEDLINE/PubMed can be challenging. For this reason, the NLM now offers automated MEDLINE/PubMed filtered searches for relevant citations. Users can also further limit their search (via checkboxes) to citations with the "Animal Use Alternatives" MeSH term, to the PubMed Toxicology Subset, and to citations published after 2000.

For information prior to 2001, users can search ALTBIB, NLM's bibliographic collection on alternatives to animal testing. It includes citations from published articles, books, book chapters, and technical reports from 1992 to 2001. The bibliography contains citations on methods, tests, assays, and procedures that may be useful in establishing alternatives to the use of intact vertebrates.

In 2001, MEDLINE incorporated several enhancements to facilitate the information retrieval of animal alternatives literature, such as adding MeSH main headings on the animal alternatives subjects and indexing more journals relevant to animal alternatives. Since the introduction of these new enhancements, ALTBIB has not been updated. (9/28/2005)

TRI2003 Released

TRI2003 was released to the public on TOXNET on June 13, 2005. The new release contains 91647 records.  (6/13/2005)

New version of TOXMAP released TOXMAP 2.4 contains the following new features:

  • 2003 Toxics Release Inventory Data (TRI)
  • Chemical Spell Checker: Chemical names are often hard to spell; TOXMAP now locates ‘near matches’
  • TRI chemical list page, with links to National Library of Medicine chemical information resources
  • Updated and expanded FAQs (7/25/2005)

ChemIDplus News

ChemIDplus Lite was recently updated to use the same Marvin generated structure display in PNG format used in our Advanced version. This has allowed immediate updating of the structures in Lite. The display of physical and toxicological data was also added at this time.

New Locators that have been added in the past months:

  • CHEBI -- Chemical Entities of Biological Interest ( ChEBI) is a freely available dictionary of small molecular entities
  • NTP DBS -- This new NTP website is a "Work-in-Progress" project. The goal of this National Toxicology Program (NTP) website is to make individual animal data from NTP studies publicly available.
  • USDA ARS -- USDA ARS PPD is a compendium of chemical and physical properties of over 330 widely used pesticides (6/9/2005)

WISER Windows™ version is now available for free downloading

An operational version of WISER for Microsoft Windows™ is now available for free download at In addition, updated versions of the WISER for PocketPC and WISER for Palm are available.

WISER is a system designed to assist first responders in hazardous material incidents. It provides a wide range of information on hazardous substances, including substance identification support, physical characteristics, human health information, and containment and suppression advice.

Feedback on WISER is welcome. (6/9/2005)

FY 2005 AIDS Community Information Outreach Projects Awarded

NLM funded 18 AIDS Community Information Outreach Projects in September 2005.



Customizing TOXMAP

TOXMAP users can now create customized maps from their own web sites by incorporating a simple web link.

Full instructions are provided in the TOXMAP FAQ entitled "How can I link my site to TOXMAP?". Examples are also included. (12/14/2004)


TOXMAP is an interactive web site that shows the amount and location of reported toxic chemicals released into the environment on maps of the United States. TOXMAP allows users to visually explore information about releases of toxic chemicals by industrial facilities around the United States as reported annually to the Environmental Protection Agency.

TOXMAP is designed to:

  • Show the geographic distribution of releases by chemical
  • Show how the amount of chemical releases have changed over time
  • Link to chemical information in TOXNET's Hazardous Substances Data Bank (HSDB) and other authoritative resources
  • Use chemical and geographic terms from the displayed map to search bibliographic databases
  • Integrate geographically coded data from other sources
  • Provide general information about GIS, data quality, and map interpretation
  • Be easy to navigate and to understand by those unfamiliar with GIS
  • Since many users may not be experienced in reading maps or understanding map data, TOXMAP provides Frequently Asked Questions (FAQs)
  • More information about TOXMAP can be found at (11/04/2004)

TRI2002 Released

TRI2002 was released to the public on TOXNET on August 31. The new release contains 93,380 records. (10/13/2004)

Advanced Version of the ChemIDplus Chemical Search Database

The Division of Specialized Information Services (SIS) of the US National Library of Medicine (NLM) announces a new Advanced version of the ChemIDplus chemical search database. It takes the place of our original ChemIDplus search page and offers more searching options and system stability.

These new capabilities provide users more advanced search options and system stability, and complement the recently released ChemIDplus Lite version which does not allow structure searching. These Advanced and Lite interfaces run against the same ChemIDplus database as before, with the addition of new chemical and biological data tables to give property searching capability.

Following are some of the highlights of this new search interface:

  • Name, CAS RN, Classification Code, Locator and Formula searching in the original ChemIDplus format for over 368,000 substances. Over 1.3 million chemical names are available as well as over 100 Locator URLs pointing other resources pertinent to a given chemical
  • Chemical Structure searching using the newest MDL ISISDirect software, by substructure, similarity, and individual structure
  • Chemical Structure display using ChemAxons Marvin product, which generates a browser friendly png (portable network graphic) image and thus doesn't require the Chime plug-in for display
  • Chemical Structure drawing input by the ChemAxon Marvin Java applet, editor, as well as the MDL Chime and ISISDraw combination
  • Numeric searching by biological endpoints, including LD50 and LC50. The user may specify Test, Species, Route, and Effect, and both ranging and exact match are available
  • Numeric chemical property search and display on eight fields such as Melting Point and Boiling Point, Water Solubility and LogP
  • Numeric molecular weight ranging and exact search
  • Tracking of your query history, including display of structures searched, and the capability to re-run or modify old searches during a session
  • Much longer session times than previously available. There is now a half hour of inactivity before the session ends (09/24/2004)

Native American Health Web Site

SIS recently launched the Native American Health Web Site, a gateway to information about issues affecting the health and well-being of American Indians. The portal brings together health and medical resources pertinent to the American Indian population including consumer health information, traditional healing, tribal web sites, environmental concerns, and disease research. Links are provided to an assortment of documents, Web sites, databases, and other resources. (8/12/2004)